What happens to nanoparticles when they enter the bloodstream?

Aug 13, 2026 - 12:11
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What happens to nanoparticles when they enter the bloodstream?
The use of nanoparticles in drug delivery offers key advantages: they can enable targeted drug delivery, protect active ingredients from premature degradation, extend their duration of action in the body and reduce side effects. However, as soon as nanoparticles come into contact with blood, proteins from the blood adsorb onto their surface—forming a so-called protein corona. This corona influences whether the particles are taken up by cells, how they distribute in the body or whether the immune system recognizes and attacks them.

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Oganews

As a passionate news reporter, I am fueled by an insatiable curiosity and an unwavering commitment to truth. With a keen eye for detail and a relentless pursuit of stories, I strive to deliver timely and accurate information that empowers and engages readers.

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